Coding

Part:BBa_K2486001

Designed by: Fabio Nunes de Mello   Group: iGEM17_USP-Brazil   (2017-10-01)


His-tagged (EPIP)4

This part is composed of four Plasmodium Enolase–Plasminogen Interaction Peptides (EPIP), a synthetic protein that inhibits the development of Plasmodium falciparum and Plasmodium berghei inside the Anopheles mosquito. It works by preventing plasminogen binding on the ookinete surface, thus inhibiting the skin tissue invasion in the mosquito midgut.

This part features a His-tag on the 5'end and a HylA secretion tag on the 3' end.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None